How many cymbalta to get high

Treatment Center Locator. Don't See Your Insurance? With just 30 days at a rehab center, you can get clean and sober, start therapy, join a support group, and learn ways to manage your cravings. Cymbalta is used to treat a variety of different problems, most notably generalized anxiety disorder and depression.

It is also prescribed to help relieve nerve pain associated with diabetes and ongoing pain due to medical conditions such as arthritis and fibromyalgia; use that contradicts prescribed instructions may constitute Cymbalta abuse. Cymbalta works by helping restore the natural balance of mood and pain-related chemical neurotransmitters in the brain.

In , Cymbalta was the seventh most prescribed drug in the United States. Taking Cymbalta can improve mood, sleep, appetite, and energy levels in consumers while simultaneously decreasing nervousness.

In addition to these benefits, the medication can produce a variety of negative and potentially harmful effects as well. These side effects can range from mild to severe and include any of the following:.

Other, less common side effects include sexual dysfunction, colitis, and liver damage. These are rare and usually only occur in chronic, long-term users. Liver damage is more likely in individuals that mix the medication with alcohol , which is why doctors recommend avoiding alcohol while taking Cymbalta. Learn More. The risk of experiencing these negative side effects is also increased when the drug is abused. Drug abuse constitutes any situation in which the medication is used either without a prescription or not as explicitly prescribed.

Many individuals will often crush the drug and mix it with liquid in order to feel the effects immediately, bypassing the extended time release capsule. Diverted use such as this increases the risk of serious complications such as abdominal cramping, convulsions, and severe skin reactions.

Like the majority of Antidepressants, Cymbalta is generally considered to be non-addictive; however, the drug can cause physical dependence.

Those that try to reduce their dose or stop taking Cymbalta altogether will start to experience uncomfortable withdrawal symptoms, which can cause some people to keep taking the drug despite wanting to quit. This leads to a cycle of addiction and dependence where individuals build up a tolerance and effectively take more and more of the medication in an effort to prevent the debilitating effects of withdrawal.

Regardless of the reason behind why someone is misusing Cymbalta, whether it be to prevent withdrawal or simply to experience the pleasurable effects of the medication, taking high doses of the drug is dangerous. Taking duloxetine with food delays time to peak levels and reduces absorption by 10 percent. Evening doses are also absorbed more slowly and less completely than morning doses.

None of these food or time variables have clinical significance; in other words, duloxetine can be taken without regard to meals. Duloxetine capsules should be swallowed whole. Do not chew, crush, or open capsules to sprinkle on food or mix with liquids. No dose reductions are recommended by the manufacturer for geriatric patients, by gender, or in smokers. In patients with renal impairment, duloxetine should be started at lower than usual doses and titrated upwards more gradually.

Duloxetine is also not recommended for patients with any degree of liver hepatic insufficiency, liver disease or heavy alcohol consumption. Fatal overdoses of duloxetine have been reported with as little as 1, milligrams. Overdoses generally manifest with sleepiness, coma, serotonin syndrome, seizures, tachycardia, hyper or hypotension, and vomiting.

Treatment should be supportive. Activated charcoal may be useful in reducing absorption. Hemodialysis is unlikely to be helpful. As in all overdoses, the possibility of multidrug ingestion should be considered.

Relief of symptoms can usually be seen within seven days to two weeks. Duloxetine is metabolized extensively in the liver, 70 percent is excreted by the kidneys and 20 percent in feces. Adverse events have been observed in fetal animal studies of duloxetine, especially during the later third trimester.

No well controlled human studies are yet available. Use during pregnancy must be carefully balanced against risks and benefits. Women treated for major depression are likely to relapse if medication is discontinued during pregnancy. Therapy should be individualized. Duloxetine is excreted in breast milk. Studies demonstrate breast fed infants receive an average of 0.

Use in breast feeding mothers should carefully weigh risks versus benefits. Duloxetine Cymbalta comes in 20, 30 and 60 milligram delayed release capsules imprinted with the dosage strength on the side of the capsule. Strengths are colored differently.

Capsules should be stored at room temperature between 68 to 77 F with occasional variations to between 59 to 86 F permitted. Cautions and Warnings — Aside from the FDA Black Box warnings on worsening of depression and risk of suicide, common sense is necessary with any patient being treated with antidepressants. Regardless of age, monitoring for clinical worsening, risk of suicide and unusual behaviors is mandatory.

Duloxetine will not affect any type of contraception, including the combined pill or emergency contraception. Some people cannot concentrate properly while they're taking duloxetine.

When you first start taking duloxetine, it's a good idea to stop driving and cycling, and avoid using machines or tools, for the first few days until you know how this medicine makes you feel. Cannabis can affect the levels of duloxetine and make you more likely to get side effects. Talk to your doctor if you think you might use recreational drugs while taking duloxetine. Page last reviewed: 31 January Next review due: 31 January Duloxetine On this page About duloxetine Key facts Who can and can't take it How and when to take it Side effects How to cope with side effects Pregnancy and breastfeeding Cautions with other medicines Common questions.

About duloxetine Duloxetine is an antidepressant medicine. Duloxetine comes as capsules and is only available on prescription. Help us improve our website Can you answer a quick question about your visit today?

Duloxetine normally takes 2 to 4 weeks to work. It may take longer if you're taking it for nerve pain. Common side effects include feeling sick, a dry mouth, headache, constipation and feeling sleepy.

These side effects are usually mild and go away after a couple of weeks. If you and your doctor decide to take you off duloxetine, your doctor may recommend reducing your dose gradually to help prevent extra side effects.

Duloxetine is also called by the brand names Cymbalta and Yentreve. Duloxetine can be taken by adults aged 18 years and over. For stress urinary incontenince, duloxetine can only be used by women. To make sure it's safe for you, tell your doctor if you: have had an allergic reaction to duloxetine or any other medicines in the past have kidney or liver problems have a heart problem are taking or have taken other medicines for depression within the last 14 days have an eye condition called glaucoma - duloxetine can increase the pressure in your eye have or have had fits, manic episodes or bipolar disorder bruise easily are trying to become pregnant, are already pregnant, or you're breastfeeding.

How much will I take? How much you take will depend on what you're taking it for: depression - the starting dose is 60mg a day and can be increased to mg a day anxiety - the starting dose is 30mg a day and can be increased to 60mg a day nerve pain - the starting dose is 60mg a day and can be increased to 60mg twice a day stress urinary incontinence - the starting dose is 20mg twice a day and can be increased to 40mg twice a day after 2 weeks What if I forget to take it?

If you usually take duloxetine: once a day - take the missed dose as soon as you remember, unless it's less than 12 hours until your next dose, in which case skip the missed dose twice a day - take the missed dose as soon as you remember, unless it's less than 4 hours until your next dose, in which case skip the missed dose Never take 2 doses at the same time to make up for a forgotten one.

If you forget doses often, it may help to set an alarm to remind you. What if I take too much? Urgent advice: Call your doctor straight away if you take too much duloxetine and:.

Common side effects These side effects happen in more than 1 in people. These are not all the side effects of duloxetine. For a full list, see the leaflet inside your medicines packet. Information: You can report any suspected side effect to the UK safety scheme. What to do about: difficulty sleeping - try taking duloxetine first thing in the morning headaches - make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller.

Talk to your doctor if they last longer than a week or are severe. If you begin to feel dizzy, lie down so you do not faint, then sit until you feel better. Do not drive or use tools or machines if you feel dizzy, have muscle cramps or muscle pain, or if you just feel a bit shaky. Cymbalta is the brand name for the drug duloxetine and it is only legally available with a prescription.

A dose comes in the form of a time-released capsule and while the typical dose is usually mg daily, some people take up to mg per day. Additionally, taking Cymbalta with other drugs or alcohol can cause serious or life-threatening side effects and long-term use of duloxetine with alcohol or Tylenol can cause severe liver damage.

Although Cymbalta is not classified as an addictive drug , discontinuation syndrome is common among people who suddenly stop using SSRI antidepressants like Cymbalta.

Discontinuation syndrome can be very uncomfortable and may cause symptoms like dizziness, numbness or tingling sensations, lethargy, problems sleeping, irritability, anxiety, irritability, nausea, and vomiting. According to Psych Central, up to 80 percent of people who quit using Cymbalta experienced discontinuation syndrome. Three decades ago, less than one in 50 Americans used antidepressants. Although Cymbalta is not addictive, people taking the drug can quickly succumb to the classic addictive behaviors and cycle of dependence because they need more of the drug to prevent the uncomfortable side effects of withdrawal.

Cymbalta abuse is rare since the drug does not cause a high when it is taken in large doses. However, if a person suddenly stops taking it, they may experience uncomfortable withdrawal symptoms and may also have suicidal thoughts. Although abuse of Cymbalta rarely happens, taking extremely large doses of the drug can cause overdose which is characterized by several severe side effects, including:. People who take Cymbalta as prescribed on a long-term basis also report experiencing weight gain.

People who have a history of severe depression or who take one or more antidepressant drugs may be more at risk of misusing or abusing Cymbalta. Some signs and symptoms of addiction and prescription drug abuse are:. If a person suddenly stops taking Cymbalta, they may experience unpleasant physical and psychological side effects known as withdrawal.

Cymbalta withdrawal symptoms include:. Although the side effects of Cymbalta withdrawal are not deadly on their own, suicidal thoughts may occur, so medical and clinical monitoring is often necessary. Additionally, since Cymbalta withdrawal symptoms can also be severe, users should rely on an experienced medical professional to gradually taper their use of the drug instead of suddenly discontinuing all use.